NCIMB launches probiotics and microbial additive testing service

NCIMB has launched a new package of services to support manufacturers of probiotic products and feed additives in assessing the suitability of candidate strains and complying with European Food Safety Authority (EFSA) FEEDAP guidelines. FEEDAP is the Panel on Additives and Products or Substances used in Animal Feed.

Our package includes a range of tests and analyses that provide valuable information about the functional characteristics of strains. Individual packages can be tailored to specific requirements. For example, strains used in probiotic products must survive the acidic gastric environment if they are to reach the small intestine and colonize the host, and our package of tests includes low pH survivability assays in simulated gastric fluid.

We also undertake mucin adhesion assessment, providing further information about the capability of strains to colonise the intestinal epithelium. The auto-aggregation ability of bacteria is key to maintaining the bacterial population within the gut and so we also offer aggregation testing within our probiotic package.

A high-quality genome sequence offers the ultimate characterisation and understanding of strains and is a key consideration in the responsible use of microbial additives with respect to limiting the spread of antimicrobial resistance in accordance with EFSA FEEDAP guidelines. We undertake genome sequencing, assembly and annotation, including prediction of antimicrobial resistance genes and virulence factors. Combining predictions from whole genome sequencing with our lab-based MIC tests helps you understand the potential of intrinsic and acquired antimicrobial resistance.

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Published: 17 Feb 2020