The role of whole genome sequencing in reducing the risk of AMR spread

As we reach the end of World AMR Awareness Week, Microbiome Services Manager Julie MacKinnon reflects on the role of whole genome sequencing in assessing strains intentionally used in the food chain to ensure they do not add to the pool of antimicrobial resistance genes in the gut. Antimicrobial resistance (AMR) is one of the top global public health threats, with bacterial AMR estimated to have been directly responsible for 1.27 million global deaths in 2019. Antimicrobial Resistance (AMR) occurs when bacteria, viruses, fungi and parasites no longer respond to …

Comparing and differentiating closely related strains of bacteria

Strain comparison and differentiation can be valuable in a range of circumstances. NCIMB’s Identification Services Manager, Vikki Warren takes a look at recent developments in the methods available for doing this and why whole genome sequencing is NCIMB’s preferred approach. Environmental monitoring is an important part of quality control in pharmaceutical manufacturing environments. When it comes to investigating incursions or process contaminants, comparing them to previous isolates and tracing their source, strain comparison and differentiation can provide valuable information over and above species level identification. If several different strains are …

Next generation sequencing: revolutionising microbiology

The development of next generation sequencing (NGS) has revolutionised genomic research, but what exactly are the benefits of NGS, and what value can it offer our customers? We take a brief look back at the development of sequencing technologies and highlights some of the applications. Microbiologists have always exploited new technologies in order to understand the impact and processes of bacterial systems. In 1977, Carl Woese revolutionised microbial taxonomy, using rRNA genes as a marker to classify archaea as a separate domain from bacteria. The same year marked the development …

NCIMB launches three-point strain health check service

Microorganisms have many applications in a diverse range of industry sectors – from traditional food and drink manufacturing to industrial biotechnology and synthetic biology. Good microbe management is crucial to ensure that processes are optimised and products meet quality requirements. To support companies in achieving this, NCIMB has launched a new three-point strain health check for microbes used as production strains, and in applications such as feed additives or probiotic products. The health check service allows organisations that use microorganisms in these ways to: Identify and assess strain functionality Monitor …

NCIMB introduces services to support sustainable manufacturing at the High Value Biorenewables Network Event

NCIMB’s Business Development Manager Dr Jude Huggan introduced delegates at the High Value Biorenewables Network 2020 event: “Discovery, development and production of high value bio-based products” to the services that NCIMB offers to support sustainable manufacturing. NCIMB offers a broad range of services to support companies working in this important and exciting field and Jude’s presentation gave attendees an introduction to how we can support sustainable manufacturing throughout the process from discovery and development to manufacturing and quality control. NCIMB’s culture collection represents a unique resource when it comes to …

NCIMB launches probiotics and microbial additive testing service

NCIMB has launched a new package of services to support manufacturers of probiotic products and feed additives in assessing the suitability of candidate strains and complying with European Food Safety Authority (EFSA) FEEDAP guidelines. FEEDAP is the Panel on Additives and Products or Substances used in Animal Feed. Our package includes a range of tests and analyses that provide valuable information about the functional characteristics of strains. Individual packages can be tailored to specific requirements. For example, strains used in probiotic products must survive the acidic gastric environment if they …