The role of whole genome sequencing in reducing the risk of AMR spread

As we reach the end of World AMR Awareness Week, Microbiome Services Manager Julie MacKinnon reflects on the role of whole genome sequencing in assessing strains intentionally used in the food chain to ensure they do not add to the pool of antimicrobial resistance genes in the gut. Antimicrobial resistance (AMR) is one of the top global public health threats, with bacterial AMR estimated to have been directly responsible for 1.27 million global deaths in 2019. Antimicrobial Resistance (AMR) occurs when bacteria, viruses, fungi and parasites no longer respond to …

Comparing and differentiating closely related strains of bacteria

Strain comparison and differentiation can be valuable in a range of circumstances. NCIMB’s Identification Services Manager, Vikki Warren takes a look at recent developments in the methods available for doing this and why whole genome sequencing is NCIMB’s preferred approach. Environmental monitoring is an important part of quality control in pharmaceutical manufacturing environments. When it comes to investigating incursions or process contaminants, comparing them to previous isolates and tracing their source, strain comparison and differentiation can provide valuable information over and above species level identification. If several different strains are …